2008 Davidson Wildcats

Streeter Lecka/Getty Images
Streeter Lecka/Getty Images
Led by future NBA legend Steph Curry, the 2008 Davidson Wildcats entered the tournament as a 10-seed, but made it all the way to the Elite Eight.
The tournament helped solidify Curry as an NBA prospect and Davidson as a legitimate threat, and the Wildcats beat powerhouses Gonzaga, Georgetown, and Wisconsin en route to a showdown with Kansas. While they lost, their run remains memorable to this day.